KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOP2B
All Species:
19.7
Human Site:
S1476
Identified Species:
30.95
UniProt:
Q02880
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02880
NP_001059.2
1626
183267
S1476
E
D
S
A
S
V
F
S
P
S
F
G
L
K
Q
Chimpanzee
Pan troglodytes
XP_516332
1634
184611
S1484
E
D
S
A
S
V
F
S
P
S
F
G
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001092092
1620
182490
S1470
E
D
S
A
S
V
F
S
P
S
F
G
L
K
Q
Dog
Lupus familis
XP_534241
2041
231068
S1893
E
D
S
A
S
V
F
S
P
S
F
G
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q64511
1612
181890
A1463
E
D
T
A
S
V
F
A
P
S
F
G
L
K
Q
Rat
Rattus norvegicus
P41516
1526
173202
A1386
D
G
K
D
S
V
P
A
S
P
G
A
S
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507216
1923
216719
S1776
E
D
S
A
P
V
F
S
S
S
F
A
L
K
S
Chicken
Gallus gallus
O42131
1627
183228
S1482
E
D
S
T
P
V
F
S
S
P
F
A
P
K
Q
Frog
Xenopus laevis
NP_001082502
1579
178601
A1438
A
P
E
P
A
P
R
A
K
V
S
S
A
K
V
Zebra Danio
Brachydanio rerio
NP_001038656
1618
182448
R1468
K
S
D
S
D
G
D
R
G
P
V
F
S
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15348
1447
164377
K1307
K
T
S
P
K
A
K
K
A
V
V
K
K
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23670
1520
172316
A1380
K
P
R
T
G
K
G
A
A
K
A
E
V
I
D
Sea Urchin
Strong. purpuratus
XP_783546
1448
163750
A1308
L
S
D
K
P
A
G
A
K
P
K
T
K
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P30182
1473
164089
D1333
S
K
A
I
A
V
D
D
D
D
D
D
V
V
V
Baker's Yeast
Sacchar. cerevisiae
P06786
1428
164196
K1288
K
D
E
G
E
L
S
K
I
S
N
K
F
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
98.5
78.1
N.A.
95.6
66.2
N.A.
79.3
89.2
66.6
73.6
N.A.
50.3
N.A.
49.5
57.3
Protein Similarity:
100
98.5
99.1
78.8
N.A.
97.2
78.1
N.A.
81.8
93.8
78.7
83.8
N.A.
64.3
N.A.
65.8
69.9
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
73.3
60
6.6
0
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
73.3
60
20
13.3
N.A.
20
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
43.3
40.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59
56.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
40
14
14
0
34
14
0
7
20
7
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
54
14
7
7
0
14
7
7
7
7
7
0
0
7
% D
% Glu:
47
0
14
0
7
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
47
0
0
0
47
7
7
0
0
% F
% Gly:
0
7
0
7
7
7
14
0
7
0
7
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
0
0
0
0
7
0
% I
% Lys:
27
7
7
7
7
7
7
14
14
7
7
14
14
60
7
% K
% Leu:
7
0
0
0
0
7
0
0
0
0
0
0
40
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
14
0
14
20
7
7
0
34
27
0
0
7
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% Q
% Arg:
0
0
7
0
0
0
7
7
0
0
0
0
0
0
0
% R
% Ser:
7
14
47
7
40
0
7
40
20
47
7
7
14
7
7
% S
% Thr:
0
7
7
14
0
0
0
0
0
0
0
7
0
7
0
% T
% Val:
0
0
0
0
0
60
0
0
0
14
14
0
14
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _